At his pre-match press conference at the training ground on Thursday the boss said: "We've had a good week training but it's not come without it's troubles.
"We're probably going to have to change things around again. It's been enforced on us. I'm not going to give the game away to the opposition and say who might be missing.
"It's frustrating, though, because all we want is a settled team to pick and it's proving to be difficult at the moment. But that's life and we'll get on with it.
"It means we've got a busy day on the training pitch today [Thursday].
"We need to be organised and when a player drops out and you change things around you need to make players understand their roles and positions."
Jake Howells, who came off with concussion in last Saturday's goalless draw with Wrexham at Kenilworth Road, is fit to travel for the game at Blundell Park.
Garry Richards is still a long-term but James Dance and Danny Spiller are three or fours weeks away from a return to action.
Full report and video to follow.