The Hatters take on Preston North End under the Kenilworth Road lights on Wednesday evening.
Looking to regain their place in the play-off positions after disappointment against QPR on Sunday, Town will have to be at their best with Preston coming into the game with a four-game unbeaten run to their name.
Preston North End have enjoyed an upturn in form since Ryan Lowe took the hotseat in December.
With three draws and a win in their last four outings, the Lilywhites have proven to be a tricky opposition, only conceding two goals in the process.
In attack, Emil Riis Jakobsen has been the big hitter in front of goal, with 17 goals to his name in all competitions.
Last time we met:
Preston were 2-0 winners back in October in the last meeting, however the fixture at Kenilworth Road last year was a more memorable one for Luton.
As well as having 2,000 home supporters back for the first time, James Collins scored a hat-trick to mark Nathan Jones' 200th match in charge with his 100th victory.
Follow the action:
UK-based fans will be able to watch the match on iFollow as this is a midweek home fixture.
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Referee: Stephen Martin
Assistant Referees: Nigel Lugg and Steven Meredith
Fourth Official: Charles Breakspear
The man in the middle on Wednesday night is Stephen Martin, who most recently took charge of Luton's 2-0 away defeat against Sheffield United.
In total he has officiated 26 matches this season, handing out 81 yellow cards and four reds.