Town boss Matt Bloomfield makes three changes to the side that lost at Lincoln last weekend.
Christ Makosso returns in defence while Shayden Morris makes his first start in Town colours following his deadline day move from Aberdeen.
Lamine Fanne comes into midfield for his second start of the season as Nigel Lonwijk, Jordan Clark and Jerry Yates miss out through injury.
Marvelous Nakamba returns to the Hatters squad for his first involvement in the squad since the end of last season.
Town: Keeley, Makosso, Naismith, Mengi, Andersen, Saville, Fanne, Morris, Alli, Nelson, Wells.
Subs: Shea, Nakamba, Nordås, Richards, Kodua, Gbodé, Bramall.