Town boss Rob Edwards makes one change to the side that beat Newcastle on Saturday with Ryan Giles replacing the injured Issa Kaboré in defence.
The Burkina Faso picked up a knock in the first half of the 1-0 victory and former Middlesbrough man Giles comes in on the left-side of defence with Alfie Doughty moving across to the right.
It’s the only change from the win, with Amari’i Bell fit to start after being withdrawn in the closing stages of Saturday’s win.
Marvelous Nakamba is ruled out with a knee issue while Jordan Clark misses out through illness.
Sheffield United boss Chris Wilder makes four changes to the side that drew 1-1 at Aston Villa on Friday.
Town: Kaminski; Doughty, Giles, Osho, Mengi, Bell; Lokonga, Barkley; Townsend, Adebayo, Brown.
Subs: Shea, Andersen, Ogbene, Berry, Morris, Woodrow, Chong, Mpanzu, Krul.
Sheffield United: Foderingham, Baldock, Trusty, Hamer, McBurnie, Archer, Ahmedhodzic, Robinson, Souza, McAtee, Brooks.
Subs: Davies, Lowe, Brewster, Norwood, Osborn, Slimane, Osula, Norrington-Davies, Seriki.
Referee: Sam Allison