Manager Rob Edwards has made six changes from the league win against Stoke City at the weekend for tonight's Emirates FA Cup replay against Grimsby Town.
Elliot Thorpe makes his first Luton start of the season after coming off the bench three times earlier in the season prior to a loan spell with Burton Albion.
Fred Onyedinma has had a big impact since his return from injury and is in the starting line-up for the first time since October when he played over an hour against Norwich City.
Edwards has named a midfield three of Louie Watson, Allan Campbell and Luke Berry, whilst Cauley Woodrow joins Elijah Adebayo up front, the latter who scored against Grimsby last time out.
Amongst the substitutes is 17-year-old Axel Piesold. The former Tottenham Hotspur U18s midfielder recently signed a development contract with the Hatters after impressing on an extended trial from Dunstable Town.
We would like to thank the Blues for their assistance in enabling us to take Axel on trial earlier this season and subsequently sign him.
16-year-old left-back Joe Johnson is one of nine names on the bench having played in last night's FA Youth Cup Fifth Round match against Preston North End.
Luton Town: Horvath; Thorpe, Osho, Lockyer (C), Bell, Onyedinma; Watson, Campbell, Berry; Woodrow, Adebayo.
Substitutes: Shea, Morris, Burke, Mpanzu, Clark, Pepple, Doughty, Piesold, Johnson.
Referee: Sam Barrott