O'Donnell, Hall, McQuoid, Smith and Marriott all startCaretaker manager Andy Awford makes fives changes to the side that lost 2-0 at home to Wycombe on Boxing Day.
Stephen O'Donnell makes his first appearance since 26th September while Ryan Hall starts his first League 2 game since August.
Jonathan Smith also returns to the side in central midfield and there are also starts for Josh McQuoid and Jack Marriott.
The Town line-up 4-4-2: Tyler; O'Donnell, Howells, Cuthbert, Okuonghae; Smith, Lawless, Hall, McQuoid; Benson, Marriott.
Town subs: Justham, McGeehan, McCourt, Long, Mackail-Smith, Guttridge, Mackail-Smith, Wilkinson.
Pompey: Murphy, Davies, Stevens, Doyle, McNulty, Lavery, Barton, Clarke, Bennett, Evans, Hollands.
Portsmouth subs: Bass, McGurk, Roberts, Stockley, Tollitt, Chaplin, Close.
Ref: Gavin Ward.