Two towering Janos Kovacs headers gave the Hatters an impressive 2-0 win against Championship Ipswich.
The hosts played some nice passing football in the first-half, and probably deserved their 1-0 lead at the break, Kovacs heading in from a Jake Howells corner.
Ipswich enjoyed the majority of possession in the second period, but Kovacs headed in a second from a Greg Taylor cross to earn Paul Buckle's men a morale-boosting win ahead of the upcoming season.
Luton made two changes from the side that drew against Wycombe, with Kovacs and Alex Lawless coming into the starting eleven in place of Adam Watkins and JJ O'Donnell.
Town lined up with Taylor and Lathaniel Rowe-Turner right and left-backs respectively, with Ronnie Henry alongside Kovacs at the centre of defence.
The Tractor Boys meanwhile fielded a strong side, including the likes of Jimmy Bullard, Michael Chopra and former Luton favourite Andy Drury.
Luton had possession in the early stages, but Ipswich threatened first, Mark Tyler having to tip a deep Joe Whight cross over the bar for a corner in the fifth minute.
Town were playing some nice passing football and almost took the lead after ten minutes, with first Gray missing Rowe-Turner's cross, then Scott Rendell's effort being deflected wide.
In an end-to-end opening, Chopra connected with Jack Ainsley's ball into the box, but could only direct an effort straight at Tyler.
After 12 minutes, Gray thought he had put the hosts ahead after placing the ball past Scott Loach in the Ipswich goal after latching on to Howells' ball, but it was ruled out for offside.
The Hatters took the lead in the 36th minute, Kovacs powerfully heading in from a Howells corner, the ball going into the top corner with Drury unable to clear off the line.
And just before the break the hosts had Tyler to thank for two great saves, firstly parrying a Bullard strike from 25 yards, before denying Ryan Stevenson from the rebound.
Luton made one sub at the break, with O'Donnell coming on for Rendell, while Paul Jewell's visitors made six changes, including former Hatter Carlos Edwards coming on.
In the 51st minute, Tyler pulled off a great save to deny Luke Hyam's effort from the edge of the box as the Hatters maintained their lead.
Ipswich enjoyed more of the play in the second half, but Luton's defence held firm and the hosts doubled their lead with just one minute remaining.
The Hatters earned a free-kick down the left which Taylor whipped in, where Kovacs met the ball powerfully, his header cannoning off the underside of the bar and into the net.
The win provides a great foundation for Luton, who face Gateshead in their first fixutre of the Blue Square Bet Premier in two weeks time.
Luton: Mark Tyler; Ronnie Henry (Dean Beckwith 71), Lathaniel Rowe-Turner (Adam Watkins 56), Janos Kovacs, Greg Taylor; Jake Howells (Matt Robinson 77), Yaser Kasim, Alex Lawless; Stuart Fleetwood (Jake Woolley 68), Scott Rendell (JJ O'Donnell 46), Andre Gray (Dan Walker 68)
Subs not used: Dean Brill