Kal Naismith makes his first start for the Hatters after coming off the bench in the last two league matches as Dan Potts starts amongst the substitutes.
Captain Sonny Bradley remains in defence and alongside him is Glen Rea and Tom Lockyer – the latter whose red card against Brentford was over-turned.
Ryan Tunnicliffe comes into midfield to support Pelly-Ruddock Mpanzu and Kiernan Dewsbury-Hall, whilst Jordan Clark is the fourth and final change – who starts up-front with Harry Cornick.
Town: Sluga; Bree, Lockyer, Rea, Bradley (C), Naismith; Mpanzu, Tunnicliffe, Dewsbury-Hall; Clark, Cornick.
Substitutes: Shea, Potts, Berry, Hylton, Lee, Moncur, Collins, LuaLua, Nombe
Chelsea: Kepa, James, Christensen, Zouma, Emerson; Pulisic, Mount, Gilmour, Ziyech; Werner, Abraham.
Substitutes: Caballero, Rudiger, Jorginho, Kovacic, Giroud, Hudson-Odoi, Chilwell, Azpilicueta, Havertz.
Referee: David Coote