The Hatters fell to another defeat on the road as they were beaten 2-0 at Ewood Park.
In-form Rovers’ sixth successive win was secured thanks to two first-half goals from Amario Cozier-Duberry and Owen Beck.
The Town had chances in both halves to cut the deficit but their chances of a comeback were dashed following Liam Walsh’s second red card of the season with 17 minutes remaining.
It began with Rob Edwards naming an unchanged side following Tuesday’s win over Stoke but clear-cut chances were few and far between in the opening quarter.
However, Rovers had looked threatening in the opening exchanges with Cozier-Duberry a menace on the right flank – and it was the on-loan winger who opened the scoring just after the half-hour mark. Makhtar Gueye was the creator, bursting in the box to lay the ball off to Cozier-Duberry whose low shot crept into the bottom corner.
The Hatters’ response to going behind was excellent and within two minutes of trailing they came close to a leveller. Firstly Elijah Adebayo’s low shot was parried away by Aynsley Pears in the Rovers goal and the home goalkeeper then kept out Tahith Chong’s on-target follow-up.
But just when the Town sensed an equaliser, Blackburn doubled their lead five minutes before the break. Joe Rankin-Costello raced down the right and his cross seemed set to be converted by Gueye with the goal at his mercy. The Rovers striker completely fluffed a guilt-edged chance from six yards but the ball spun kindly into the path of Beck who thundered a finish past Thomas Kaminski.
The Hatters number one stopped Rankin-Costello’s shot on 43 minutes and Harry Pickering flicked an effort inches wide in first-half stoppage time as the hosts ended the half in the ascendency.
Behind at the break the Town started the second half well, and Carlton Morris wasn’t far away with a looping header five minutes after the restart following Jordan Clark’s right-wing deep cross.
Jacob Brown then sent a low shot on the turn wide of the mark on 51 minutes as the Hatters continued to search for a way back into the game.
As the Town pressed in a bid to halve the deficit, Morris came mighty close to making it 2-1 shortly after the hour when turning brilliantly in the box and sent a shot on the turn millimetres wide of the post.
But the Hatters’ hopes of mounting a comeback looked bleak on 73 minutes when Walsh was red-carded for a late, rash challenge on Rovers’ Yuki Ohashi.
As time ticked down Rovers ended the stronger with former Rovers stopper Kaminski having to repel efforts from substitutes Ryan Hedges and Harry Leonard and prevent a third.
But the Walsh red card knocked the stuffing out of the Town and the final whistle signalled a seventh straight away defeat.
Town: Kaminski; Chong, Moses (sub Nelson 86), Hashioka (sub Johnson 77), McGuinness, Holmes; Clark, Krauß (sub Walsh 62); Brown (sub Woodrow 62), Morris (sub Taylor 86), Adebayo.
Subs not used: Krul, Andersen, Nakamba, Mpanzu.
Attendance: 13,857, including 705 Hatters in the away end.
