The Hatters' penultimate home game of the season comes against a Wycombe Wanderers side that appeared destined for automatic promotion after spending the majority of the campaign in pole position, only for the club to suffer an untimely blip during the last two months.
Peter Taylor's men have, however, managed to climb back up to third position and have a game in hand over their rival promotion challengers. After only winning one of their seven matches in March - picking up seven points out of a possible 24 - the Chairboys' form must improve if they're to end the season inside the top three.
Wycombe's steely defence was the main reason why they occupied top spot for so long. With clean sheets in almost half of their league matches and the best defensive records at both home and away from Adams Park, Taylor's men have only lost on six occasions this season, and had only lost once before January.
It's in the final third where the Buckinghamshire club have been less effective. Matt Harrold is the current top scorer but is still looking to make it double-figures for league goals. The rest of the goals have been split evenly amongst Wycombe's large squad of players, but the Chairboys have rarely looked lethal in front of goal during this campaign.
The Hatters last met Wycombe back in December at Adams Park, where Mick Harford's side earned a credible goalless draw against the club when they were riding high at the top of the league.
Scott Shearer earned Taylor's side a clean sheet that afternoon but will miss this match because of an ankle injury. Despite this, the Chairboys have two very capable replacements in the form of either Jamie Young or highly-rated 19-year-old goalkeeper Marek Stech. The Czech youth international is currently on-loan from West Ham and could be between the sticks at Kenilworth Road on Tuesday night.
Elsewhere, John Akinde will be a threat if his loan is extended until the end of the season. The striker from Bristol City scored three goals in four matches last month. While Chelsea have allowed another highly-rated 19-year-old join the club, in the form of attacking midfielder Lee Sawyer.
The two clubs have met 16 times in total. The Chairboys are looking for only their second ever win over the Hatters. Luton have won on eight occasions and seven matches have ended all square.