Luton: Drew Talbot and Ed Asafu-Adjaye are added to the Hatters squad that drew at Wycombe at the weekend.
Colchester: The U's will be without left back Marc Tierney who his cup tied and Jermaine Easter who has returned to parent club Plymouth.
Mick Harford (talking to lutontown.co.uk): "It will be a tough game and I'm sure Paul Lambert will be wanting to progress.
"I have told the players that we are close to Wembley, it's never an easy step but, if we can get a victory tomorrow evening, we're that step closer.
Chris Coyne (talking to tonight's matchday programme): "I'm glad this fixture has come up because you never know when you're going to have the opportunity to go back to your old club. I see this as a good opportunity to come back and see old faces as well as old friends I've kept in touch with."
You can read this interview in full in tonight's matchday magazine, available from the normal locations for £3.
| One to watch - Mark Yeates |
There was no question Mark Yeates was going to be a footballer. Growing up in Ireland with a dad who played for Shelbourne and Shamrock Rovers amongst others, he got the bug early on, starting his career with Tottenham Hotspur.
Chances at White Hart Lane were limited so the Irish U21 midfielder went out on loan to Swindon before making three appearances for the Premier League side. He spent 2005/06 out on loan at Colchester, scoring five goals in 44 appearances as they achieved promotion to the Championship.
He returned to Spurs, where he signed a new two-year deal before going out on loan again, this time to Hull City where he struggled to make a real impact. He then enjoyed a loan spell at Leicester before leaving Spurs in the summer and returning to the U's.
The 23-year-old signed permanently in July 2007, for an undisclosed six-figure sum. Since returning he has played over 50 games and scored 15 goals.
Colchester form: LWWLL
Before Saturday's trip to Leeds United, Colchester sat in 16th place in League One, three points above the relegation zone. Their main problem this season has been their difficultly in adjusting to the surrounding of their new Community Stadium.
The U's have only won twice in front of their home supporters and have managed just ten goals in their ten games at their new home.
More recently, consecutive defeats to Peterborough and Walsall were followed by two successive wins over Yeovil (1-0) and Northampton (2-1).
But the 2-1 defeat at home to Hereford on 6th December was their sixth at home and tenth overall.
Luton wins: 8
Colchester wins: 5
Draw: 9
Despite only meeting 22 times, games between the two sides have always generated plenty of goals. In fact, on average, almost three goals are scored every time the teams meet.
The Hatters biggest victory over Colchester occurred at Layer Road in April 2003 when a Steve Howard hat-trick inspired the Town to a 5-0 win.
Of Colchester's five wins, two have been at Kenilworth Road. The last was back in December 2002 when Dean Morgan scored the winner for the U's in a 2-1 victory.
It was Boxing Day 2006 when the two sides last met when both teams were playing in the Championship. That season was Colchester's first at that level where they eventually finished in 10th place. The Hatters, meanwhile, were relegated.
And this result hardly helped the Town's cause as Colchester ran out easy 4-1 victors. Two goals from Chris Iwelumo and further strikes by Richard Garcia and Kevin McLeod sealed a comprehensive victory. Rowan Vine pulled a goal back with five minutes left for the Town from the penalty spot.
Colchester: Gerken, Halford, Baldwin, Wayne Brown, Barker, Garcia, Watson, Izzet, McLeod (Jackson), Cureton (Ephriam), Iwelumo (Guy). Subs not used: Davison, Richards.
Luton: Kiely, Foley, Heikkinen Coyne, Emanuel (Davis), Edwards (Feeney), Bell, Barnett, Brkovic, Vine, Morgan. Subs not used: Beresford, Langley, Holmes.
Attendance: 5,427
The U's' relegation from the Championship last season meant the club slipped back into League One for the first time since finishing runners-up to Southend in 2005/2006.
Their two-season stay in the second tier was the first time ever Layer Road had hosted football at that level.
They finished three points behind their Essex rivals when winning promotion but after a 10th place finish in their debut season they finished bottom in the next, 15 points from safety.
Before their elevation to the Championship, Colchester had enjoyed several steady seasons in League One before their success in 2006.
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