Preston v Southampton - Monday March 5th, ko 8.00pm

Preston should make home advantage pay but the Saints are the top away scorers in the league, so expect plenty of goals on the night. Our Prediction: 3-2 @ 28/1

Liverpool v Barcelona - Tuesday March 6th, ko 7.45pm

Liverpool's home record this season has been built on solid defending and they'll happily settle for a draw here. Our Prediction: 0-0 @ 6/1

Arsenal v PSV - Wednesday March 7th, ko 7.45pm

Arsenal have not lost in 20 matches at the Emirates and they've beaten better sides than PSV there this season. Our Prediction: 2-0 @ 5/1

Newcastle v AZ Alkmaar - Thursday March 8th, ko 7.30pm

Newcastle face a tricky UEFA Cup tie against a useful Dutch side and they might be frustrated on the night. Our Prediction: 1-1 @ 11/2*

*If your correct score bet on this game is a winner, you won't have to wait long for [ClubBet]'s next 'Big Match' - Birmingham v Derby on Friday night.

Plus, you can also bet In-Play on the above games via Hatters Bet's In-Play Console available on the homepage so, when it come to betting on this week's 'Big Matches', there's only one place to go.